Compositions and Methods for Treating Internal Bleeding and Hemorrhage
AssigneeThe Government of The United States, as represented by The Director of the Defense Health Agency
InventorAlexander Hayes Penn
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Abstract
Disclosed herein are resuscitation fluids and compositions comprising NEFA free blood serum albumin and hemoglobulin (cell free or as lysed red blood cells) and methods of treating internal bleeding and hemorrhage.
Claims18
A composition which comprises (a) a blood serum albumin, (b) a hemoglobulin, and (c) a total non-esterified fatty acid (NEFA) content of 0.14 wt % or less of the total weight of the blood serum albumin.
A method of treating a subject for internal bleeding and/or hemorrhage, which comprises intravenously administering to the subject a blood serum albumin and a hemoglobulin, and, optionally, an amount of non-esterified fatty acids (NEFAs) that is not more than 0.14 wt % of the administered amount of the blood serum albumin.
A kit comprising (a) a blood serum albumin containing 0.14 wt % or less of NEFAs, and (b) a crystalloid, a hemoglobulin, and/or lysed red blood cells packaged together.
Dependencies are inferred from the claim text.