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US 2025/0367165 A1Published application
Emergency eye wash
AssigneeLebrun Labs LLC
InventorsStewart Lebrun, Linda Nguyen
Life of this patent
Estimating the term…
Abstract
Immediate (e.g., within 10 minutes) high volume (e.g., more than 10 mls, 100-1000 mls preferred) washing of the eye for 1-15 minutes or more with a low concentration (e.g., 5-17 mM) of a freshly made ascorbate solution with a pH between 6 and 6.99 after chemical exposure, for example after accidental or malicious splash or spray, results in significantly reduced eye damage. Products, devices and methods are provided.
Claims17
A method of reducing extent and depth of keratocyte injury in a stroma of a cornea of a subject, which cornea has been exposed to a strong oxidizing and/or corrosive chemical ocular toxin, comprising:
- identifying a subject as having a cornea that has been exposed to a strong oxidizing and/or corrosive chemical;
- rapidly mixing, within 10 minutes or less of the cornea having been exposed to a strong oxidizing and/or corrosive chemical but not prior thereto, an amount of a solid ascorbic acid or ascorbate and a buffered liquid component comprising a pH buffer and deionized water, so as to make a fresh buffered eye wash solution of 0.1% to 0.3% ascorbic acid with a pH of 6.0 to 6.99±0.5;
- and
- washing the cornea within 10 minutes or less of the cornea having been exposed to a strong oxidizing and/or corrosive chemical for a period comprising 1-15 minutes, with at least 100 mL to 1000 mL of the buffered eye wash solution,
- wherein the ascorbic acid-containing buffered eye wash solution applied to the cornea is not premixed prior to the exposure of the cornea to the strong oxidizing and/or corrosive chemical ocular toxin,
- so as to reduce the extent and depth of keratocyte injury in a stroma of a cornea exposed to a strong oxidizing and/or corrosive chemical ocular toxin.
3 more elements
Dependencies are inferred from the claim text.