Methods for treating acute conditions using lipid binding protein-based complexes
AssigneeAbionyx Pharma SA
InventorsCyrille TUPIN, Constance PEYROTTES, Ronald BARBARAS, Stanislas FAGUER
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Abstract
Methods for treating acute conditions (e.g., acute conditions comprising acute inflammation), such as cytokine release syndrome, sepsis and acute kidney injury using lipid binding protein-based complexes.
Claims56
A lipid binding protein-based complex for use in a method of treating an acute condition, wherein the method comprises administering a high dose of the lipid binding protein-based complex to a human subject in need thereof in a single dose or a plurality of individual doses administered no more than one day apart, optionally wherein the acute condition comprises acute inflammation.
An Apolipoprotein A-1 (“ApoA-1”) formulation comprising ApoA-1 and one or more lipids wherein the ApoA-1 and the lipids are in the form of lipoprotein complexes for use in a method of treating an acute condition, wherein the method comprises administering a high dose of the formulation to a human subject in need thereof in a single dose or a plurality of individual doses administered no more than one day apart, optionally wherein the acute condition comprises acute inflammation.
Dependencies are inferred from the claim text.