Dynamic laser stabilization and calibration system

A method of controlling the output of a laser ablation system, wherein the laser ablation system includes a laser and a catheter configured to be operatively coupled to the laser, the method comprising:

• receiving, at a controller of the laser ablation system, an indication to activate the laser ablation system at a chosen power output level, the laser ablation system comprising an internal sensor configured to measure an energy of at least a portion of a laser beam generated by the laser ablation system before being transmitted to the catheter, wherein the chosen power output level has pre-configured set of initial settings and that results in the laser ablation system being activated in a start-up period at a respective power output level that is less than the chosen power output level;
• sending during the start-up period, from the controller, a control signal to activate the laser ablation system using the pre-configured set of initial settings associated with the chosen power output level;
• and
• during the start-up period, iteratively (i) receiving an output from the internal sensor and (ii) adjusting at least one setting of the pre-configured set of initial settings based in-part on the output from the internal sensor and a threshold sensor level that is associated with the chosen output level, wherein the iteratively (i) receiving and (ii) adjusting in the start-up period dynamically adjust power output of the laser ablation system.