Method and kit for monitoring anticoagulant therapy
AssigneeFiix Diagnostics
InventorsPall T. ONUNDARSON, Brynja R. GUDMUNDSDOTTIR
Life of this patent
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Abstract
A method and kit are provided for measuring and monitoring a combined effect of an anticoagulant drug on coagulation factors II and X in a patient taking the anticoagulant drug. The method includes adding one or more coagulation reagents with the factor VII to a test sample and determining blood clotability of the test sample by measuring an influence of factors II and X.
Claims16
A method for measuring and monitoring a combined effect of an anticoagulant drug on coagulation factors II and X in a patient taking the anticoagulant drug, the method comprising:
- obtaining a test sample from the patient;
- mixing factor VII into one or more coagulation reagents that activate factor X through factor VII and bypasses factor IX;
- adding the one or more coagulation reagents with the factor VII to the test sample;
- and
- determining blood clotability of the test sample by measuring an influence of factors II and X.
A test kit for measuring activity of an anticoagulant drug in a patient, the test kit comprising:
- a coagulation reagent;
- factor VII;
- and
- a calcium reagent;
- wherein the coagulation reagent, factor VII, and calcium reagent are mixed together in a single container.
A method of making a point of care assay that measures activity of an anticoagulant drug in a patient, the method comprising:
- providing a coagulation reagent configured to directly activate factor VII but not factor IX;
- mixing the coagulation reagent together with factor VII to create the point of care assay;
- and
- supplying the point of care assay in a single container.
Dependencies are inferred from the claim text.