Benzene sulfonamide thiazole compounds and their use for the treatment of cancers

A benzene sulfonamide thiazole compound of formula (I):

• wherein
• R1 is a 5-(dimethylamino)naphthalene group or a 4-pentylphenyl group;
• R2 is selected from H, halogen;
• and OR6;
• R3 is selected from C1-C8 alkyl;
• and NR4R5;
• R4 is selected from H;
• and alkyl optionally substituted with a nitrogen-containing heterocycle;
• R5 is selected from H, alkyl optionally substituted with a nitrogen-containing heterocycle, and COR7;
• R4 and R5 alternatively form together a nitrogen-containing heterocycle which is optionally substituted;
• R6 is selected from C1-C8 alkyl and C1-C8 alkyl-O—C1-C8 alkyl,
• R7 is selected from
• C1-C8 alkyl optionally substituted with
• a nitrogen-containing heterocycle which is optionally substituted
• O-alkyl, NHCO-alkyl, NHCOO-alkyl, COO-alkyl, NH-alkyl, NH-alkyl-OH, NHP(O)(O-alkyl)2, NH-alkyl-SO3H, NH-alkyl-N(alkyl)2 and
• alkenyl.