Recombinant foot-and-mouth disease virus type o for inducing robust adaptive immune response and overcoming maternally-derived antibody interference, and foot-and-mouth disease vaccine composition comprising same

Abstract

Proposed are a foot-and-mouth disease vaccine composition including recombinant foot-and-mouth disease viruses and an antigen isolated and purified from the viruses. In the early stages of vaccination, a humoral immune response is simultaneously induced through the induction of a robust cellular immune response, while in the presence of maternally-derived antibodies (MDAs), B cell receptors are stimulated. Through this, it is possible to provide the vaccine composition that enables active immunity and overcomes the interference of the maternally-derived antibodies and to provide a method of preventing or treating foot-and-mouth diseases using the same composition.

Dependencies are inferred from the claim text.