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US 2025/0345484 A1Published application
Methods of isolating and using descemet's membrane and compositions including isolated descemet's membrane
AssigneeRegents of the University of Minnesota
InventorsJoshua Honghan Hou, Peter Bedard, Ching Yuan
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Abstract
This disclosure describes methods of preparing a decellularized Descemet's membrane and an isolated Descemet's membrane, methods of using an isolated Descemet's membrane, and tissues prepared using an isolated Descemet's membrane. This disclosure further describes a composition that includes an isolated Descemet's membrane. In some embodiments, the tissues and methods described herein may be used to treat a limbal stem cell deficiency or as an ocular surface bandage.
Claims9
1-23. (canceled)
A composition comprising:
- an isolated Descemet's membrane, wherein the Descemet's membrane has been decellularized and separated from the corneal stroma;
- and
- a limbal stem cell,
- wherein the limbal stem cell is in contact with the isolated Descemet's membrane.
1 more element
(canceled)
(canceled)
Dependencies are inferred from the claim text.