Pharmaceutical for the inhibition of cellular proton pumps
OwnerMohamad Kourghiinventor
Life of this patent
Estimating the term…
Abstract
The present invention provides technologies relating to modulation of voltage-gated ion channels. Particularly, the present invention provides pharmaceutical compounds for inhibiting ion transport by a voltage-gated ion channel in a subject in need thereof. In certain embodiments of the invention, the ion is a proton and the voltage-gated ion channel is a voltage gated proton channel such as Hv1. The invention further provides methods of administering a therapeutically effective amount of the pharmaceutical compounds to a subject to block the proton transport by a voltage-gated proton channel such as Hv1.
Claims8
A composition of matter, comprising a molecule of the structure I:
A composition of matter, comprising a molecule of the structure II:
A method of inhibiting proton transport by a Hv1 channel comprising:
- administering to a subject a therapeutically effective amount of a pharmaceutical composition that is capable of inhibiting proton transport by the Hv1 channel;
- wherein the pharmaceutical composition comprises a molecule of the structure I or the structure II:
Dependencies are inferred from the claim text.