Methods of treating mycobacterial infections using tetracycline compounds
AssigneesParatek Pharmaceuticals, Inc., The United States Government as represented by the Department of Veterans Affairs
InventorsMichael Henry Cynamon, Michael P. Draper, Judith N. Steenbergen, S. Ken Tanaka
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Abstract
The present invention provides methods of treating mycobacterial infections or mycobacterial diseases by administering a tetracycline compound, e.g., omadacycline, or a pharmaceutically acceptable salt thereof.
Claims21
1-195. (canceled)
A method of treating or preventing a pulmonary disease in a subject in need thereof, said method comprising administering to said subject an effective amount of omadacycline represented by formula (5):
- or a pharmaceutically acceptable salt thereof, wherein said pulmonary disease is caused by an infection with a rapid-growing nontuberculous Mycobacterium (NTM).
A method of controlling or reducing the advancement, severity or effects of a pulmonary disease in a subject in need thereof, said method comprising administering to said subject an effective amount of omadacycline represented by formula (5):
- or a pharmaceutically acceptable salt thereof, wherein said pulmonary disease is caused by an infection with a rapid-growing nontuberculous Mycobacterium (NTM).
Dependencies are inferred from the claim text.