Coatings for biological interface on implants
AssigneeBattelle Memorial Institute
InventorsAnthony D. Duong, Erik W. Edwards
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Abstract
Disclosed herein are coatings made from a biocompatible controlled release polymer and an active component. The active component can be, for example, an antimicrobial agent, an immune modulating agent, a cell signaling factor, or a growth factor. The coating has micrometer and nanometer scale features on the surface thereof.
Claims20
A coating having an outermost surface with exposed features thereon, the coating comprising a biocompatible controlled release polymer and at least one active component;
- wherein the features include micrometer scale features and nanometer scale features that rise above the outermost surface of the coating, and wherein the outermost surface is also exposed.
A method of forming a coating having a surface with exposed features thereon, comprising:
- forming a coating upon a substrate;
- the coating comprising a biocompatible controlled release polymer and at least one active component;
- and
- forming the exposed features on an outermost surface of the coating, wherein the features include micrometer scale features and nanometer scale features that rise above the outermost surface of the coating, and wherein the outermost surface is also exposed.
A medical implant having a surface with a coating thereon;
- the coating having an outermost surface with exposed features thereon, the coating comprising a biocompatible controlled release polymer and at least one active component;
- wherein the features include micrometer scale features and nanometer scale features that rise above the outermost surface of the coating, and wherein the outermost surface is also exposed.
Dependencies are inferred from the claim text.