LysECD7 VARIANTS AND METHODS OF USING THE SAME

Abstract

The present disclosure relates to a group of Antimicrobial peptides (referred to as “LysECD7 variants” or “LysECD7 variant proteins”) that are based on the wild-type enzyme LysECD7 but with specific amino acid substitutions, poly nucleotides and vectors encoding the same, peptide fragments thereof, cells or spores expressing the poly nucleotide or vector, and methods of using and making the same. In addition, the present disclosure relates to spore-associated or microbe-associated LysECD7 variants. The association of LysECD7 variants with spores or microbes can include surface display by covalent or noncovalent association or by mixing. The present disclosure is further directed to fragments or subsequences of LysECD7 variant nucleic acids comprising hybridizable portions of the LysECD7 variant sequence which have use. e.g. in nucleic acid-based assays.

Dependencies are inferred from the claim text.