US 2025/0320447 A1Published application

Centrifugal impact-based bioaerosol enrichment device, and cell exposure and use thereof

AssigneesLiaoning Technical University, Guangdong University of Technology

InventorsTing ZHANG, Taicheng AN, Guiying LI

Life of this patent

Estimating the term…

Loading patent…

Abstract

Disclosed are a centrifugal impact-based bioaerosol enrichment device, and cell exposure and use thereof. The device includes a bioaerosol enrichment device main unit and a cell exposure system; air sequentially passes through an enrichment chamber, a balance pool, and an exposure module of the enrichment device main unit; the cell exposure system collects and adjusts exposure data of bioaerosols in the air in real time; a magnetic levitation mechanism drives a cell exposure membrane box to rotate. The steps of real-time collection, intelligent adjustment, dynamic control and exposure are sequentially carried out to perform air bioaerosol enrichment and dynamic monitoring of cell exposure toxicity. The bioaerosol enrichment device, and the cell exposure and use thereof according to the present disclosure have simple and easy-to-perform methods, reliable data, and high accuracy; solve problems about enrichment and mobile monitoring of low concentration bioaerosols (including viruses, bacteria, fungi, and the like on particles) in the air; can be applied to crowd activity places such as transportation vehicles, livestock farms, biological laboratories, and residential areas; and have great application value.

Claims9

Dependent claims

A mobile centrifugal impact-based bioaerosol enrichment device, comprising a mobile centrifugal impact-based bioaerosol enrichment device main unit and a cell-based biosensor system, wherein an air inlet of the enrichment device is communicated with air and comprises an enrichment chamber, a balance pool, an exposure module, and the cell-based biosensor system;

through the air is communicated with the air inlet of the enrichment device, passes through a flexible pipeline, a micro valve, and a wireless sensor after sequentially passing through a heavy dust bin, a trace dust bin, and a microbial enrichment bin, and is connected to a bottom inlet of the balance pool;
a concentration of the bioaerosols in the air is adjusted through a filter mesh, an atomizer, and an electrostatic generator, and then the air is connected to the exposure module with a rubber piece and a sleeve sealing structure through a throttle element and an adjustment valve;
a driving mechanism and a mobile digital stand together drive a cell exposure membrane box to rotate to expose cells;
the cell exposure membrane box is supported by a 3D grid;
microtubes of the 3D grid penetrate out of the sleeve sealing structure and is connected to the cell-based biosensor system to dynamically adjust exposure conditions;
and finally, the air is emitted from an air outlet in compliance with a standard.

3 more elements

Dependencies are inferred from the claim text.