Micro-volume injectors with dose guidance and methods for use

A method for delivering a medicament into a patient's body, comprising:

• loading a volume of medicament into an interior of a syringe cartridge comprising a piston slidably disposed within the interior and a cannula;
• coupling the syringe cartridge to a driver, thereby coupling a plunger of the driver to the piston;
• inserting the cannula into the patient's body;
• activating an actuator of the driver to advance the plunger, thereby advancing the piston to deliver medicament from the interior into the patient's body whereupon one or more sensors measure displacement of the plunger, signals from the one or more sensors are analyzed to measure volume of medicament delivered from the cannula based at least in part on the signals, and an output is provided related to the volume of medicament delivered.

An injector device for delivering a precise dose of a medicament into a patient's body by a surgeon, comprising:

• a syringe cartridge comprising a cartridge housing including a proximal end, a distal end, and defining an interior, the cartridge further comprising a piston slidably disposed within the interior for delivering a medicament within the interior through an outlet in the distal end;
• a syringe driver comprising a driver housing comprising a plunger for advancing the piston within the interior of the cartridge housing, a source of pressurized fluid, and an actuator member configured to be actuated by the surgeon for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to provide controlled delivery of a medicament from the interior of the housing, wherein the actuator member is configured such that, once a surgeon releases the actuator member, delivery of the medicament is discontinued;
• one or more sensors operatively coupled to the plunger to measure displacement of the plunger;
• a processor coupled to the one or more sensors for analyzing signals from the one or more sensors to measure volume of medicament delivered from the outlet based at least in part on the displacement of the plunger;
• and
• an output device coupled to the processor for providing one or more outputs to the surgeon related to the volume of medicament delivered from the outlet to provide confirmation when a predetermined dose of the medicament has been delivered such that the surgeon may release the actuator member to discontinue delivery of the medicament at the predetermined dose.