Methods and materials for treating obesity
OwnerAlan R. Saltiel, Wenmin Xiainventors
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Abstract
Provided herein are methods and materials for treating or reducing the risk of obesity and/or conditions associated with obesity (e.g., type 2 diabetes or hyperinsulinemia). For example, provided herein are methods and materials for inhibiting RalA to treat obesity and/or conditions associated with obesity in a subject in need thereof. In some cases, the subject has elevated expression of RalA compared to a healthy individual.
Claims17
A method of treating or reducing the risk of obesity or a condition associated with obesity in a subject in need thereof, the method comprising administering a therapeutically effective amount of a pharmaceutical composition comprising an RalA inhibitor.
A method of treating obesity or a condition associated with obesity in a subject in need thereof, the method comprising:
- a) identifying the subject as having hyperinsulinemia, type 2 diabetes, a BMI of 30 or greater, a waist-hip ratio (WHR) of greater than 1.0, prediabetes, and/or fatty liver disease,
- b) administering a therapeutically effective amount of a pharmaceutical composition comprising an RalA inhibitor.
Dependencies are inferred from the claim text.