Back to results
US 2025/0282912 A1Published application
Devices and methods for analyzing biological samples
AssigneeCellanome, Inc.
InventorsSeyedsina MOEINZADEH, Justin POELMA, Meng TAING, Frank CHARBONIER, Tarun Kumar KHURANA
Life of this patent
Estimating the term…
Abstract
Systems for analyzing biological components are provided. The systems may include a fluidic device and an energy source in communication with the fluidic device. The energy source may supply energy to the fluidic device to form a polymer matrix on or adjacent to a biological component within the fluidic device. Methods of using the systems to analyze biological components are also provided.
Claims30
A polymer precursor, comprising:
- an oligomeric domain comprising three or more arms, wherein each arm of the oligomeric domain comprises a degradable functional group and a crosslinkable functional group,
- wherein the crosslinkable functional group of an arm of the three or more arms is configured to crosslink with another crosslinkable functional group of another polymer precursor in response to a first stimulus, thereby obtaining a polymerized form of the polymer precursor, and
- wherein the degradable functional group is configured to be cleaved in response to a second stimulus, thereby solubilizing the polymerized form of the polymer precursor.
A kit, comprising:
- (a) a porogen;
- and (b) a polymer precursor comprising:
- an oligomeric domain comprising three or more arms, wherein each arm of the oligomeric domain comprises a degradable functional group and a crosslinkable functional group,
- wherein the crosslinkable functional group of an arm of the three or more arms is configured to crosslink with another crosslinkable functional group of another polymer precursor in response to a first stimulus, thereby obtaining a polymerized form of the polymer precursor, and
- wherein the degradable functional group is configured to be cleaved in response to a second stimulus, thereby solubilizing the polymerized form of the polymer precursor.
2 more elements
Dependencies are inferred from the claim text.