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US 2025/0222002 A1Published application
Methods for treating benzodiazepine misuse/use disorder
AssigneeUniversity of Mississippi Medical Center
InventorsJames K. Rowlett, David James Pearson, Farhan Kayyum Taherali, Huong Thi Thanh Nguyen
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Abstract
Disclosed are compositions and methods for treating benzodiazepine misuse and/or use disorder. A method of treating benzodiazepine misuse and/or use disorder includes administering to a subject in need thereof of an effective amount of a compound that provides both partial modulator and antagonist effects at GABAA receptors.
Claims20
A method of treating benzodiazepine misuse and/or use disorder, the method comprising:
- administering to a subject having benzodiazepine misuse and/or use disorder an effective amount of a compound comprising the structure:
A composition comprising:
- (i) a compound comprising the structure:
- and
- (ii) a non-ionic surfactant comprising:
- mono-, di-, and/or triglycerides of a C8-C10 fatty acid;
- and/or
- mono- and/or diesters of PEG and a C8-C10 fatty acid.
3 more elements
A hemifumarate salt composition comprising the structure:
Dependencies are inferred from the claim text.