Silicone material, silicone tube, implant, pharmaceutical composition, and test method for amount of drug released

An implant comprising a medicinal core and a silicone tube;

• the medicinal core comprises an active pharmaceutical ingredient, and the particle size D50 of the active pharmaceutical ingredient is 180 μm or less;
• the raw material composition of the silicone tube comprises the following components in parts by weight:
• R-vinyl silicone rubber:
• 100 parts;
• hydrogen-containing silicone oil:
• 0.3-3.0 parts;
• a reinforcing agent:
• 20-80 parts;
• a catalyst:
• ≥0.000002 parts, preferably 2×10−6−5×10−5 parts;
• wherein
• in the R-vinyl silicone rubber, R is a substituted or unsubstituted C1-C5 linear alkane or branched alkane, or a substituted or unsubstituted C6-C20 aromatic hydrocarbon;
• the content of vinyl groups in the R-vinyl silicone rubber is 0.05-0.50 mol %;
• the content of Si—H groups in the hydrogen-containing silicone oil is 0.18-1.6 mol %;
• the molar ratio of Si—H groups in the hydrogen-containing silicone oil to vinyl groups in the R-vinyl silicone rubber is (0.5-4):
• 1;
• the preparation method for the silicone tube comprises the following step:
• subjecting the raw material mixture of the silicone tube to extrusion molding.