Systems and methods to measure occlusion of blood cells in microfluidic channels

Abstract

A system and a method for measuring occlusion of blood cells flowing in microfluidic channels is disclosed. The system includes an occlusion device having one or more microfluidic channels with a predefined cross-sectional area. The one or more microfluidic channels are configured to allow flow of a plurality of blood cells of a blood sample within an interior surface of the one or more microfluidic channels. Further, at least one imager is configured to generate one or more digital holography images or videos of the plurality of blood cells transiting the one or more microfluidic channels. Further, at least one processor is configured to receive the one or more digital holography images or videos and analyze the generated one or more digital holography images or videos to quantify and/or characterize occlusions formed within the one or more microfluidic channels.

Dependencies are inferred from the claim text.