System and method for optogenetics stimulation of neural tissues on microelectrode arrays

Abstract

An optogenetic stimulation and electrophysiological recording system includes an electrophysiological device coupled to optically active neural tissue, where the electrophysiological device has a microelectrode array (MEA) configured to measure electrophysiological signals. The system also includes an optical stimulation device configured to emit light configured to stimulate the neural tissue. The system further includes a computing device coupled to the electrophysiological device and the optical stimulation device. The computing device is configured to control the optical stimulation device to emit the light to stimulate the neural tissue and simultaneously receive electrophysiological signals from the optically stimulated neural tissue through the electrophysiological device.

Dependencies are inferred from the claim text.