Genetically modified microorganism and method for producing aspartic acid
AssigneesDIC Corporation, Green Earth Institute Co., Ltd.
InventorsYuji Ishigaki, Makoto Sugimoto, Toru Nakayashiki, Yakufu Aimaier
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Abstract
A genetically modified microorganism which satisfies at least one condition selected from the group consisting of the following conditions (I) and (II). Condition (I): citrate synthase activity is reduced or inactivated compared with a wild-type microorganism corresponding to the genetically modified microorganism, and condition (II): oxaloacetate decarboxylase activity is reduced or inactivated compared with the wild-type microorganism.
Claims9
A genetically modified microorganism which satisfies the following condition (I) and at least one condition selected from the group consisting of the following conditions (III), (IV) and (VI),
- condition (I):
- citrate synthase activity is reduced or inactivated compared with a wild-type microorganism corresponding to the genetically modified microorganism,
- condition (III):
- succinate dehydrogenase activity or fumarate reductase activity is reduced or inactivated compared with the wild-type microorganism,
- condition (IV):
- lactate dehydrogenase activity is reduced or inactivated compared with the wild-type microorganism,
- condition (VI):
- pyruvate:
- quinone oxidoreductase activity is reduced or inactivated compared with the wild-type microorganism.
Dependencies are inferred from the claim text.