Mechanical circulatory support device with centrifugal impeller designed for implantation in the descending aorta

A mechanical circulation support device for implantation within a descending aorta in a heart of a patient, the device comprising:

• a mechanical body having an inlet, an outlet, and an internal volume, and
• an impeller positioned within the internal volume, the impeller comprising a plurality of blades arranged around a longitudinal axis, the plurality of blades defining an outer circumference,
• wherein the inlet is configured to be placed in the descending aorta and the outlet is configured to be placed in the descending aorta downstream of the inlet,
• wherein the mechanical circulation support device is configured to have an outflow condition, the outflow condition selected to emulate a vortex in a healthy native descending aorta, and
• wherein the mechanical circulation support device is configured to work in series with the heart.

A mechanical circulation support device for implantation within a descending aorta in a heart of a patient, the device comprising:

• a mechanical body having an inlet, an outlet, and an internal volume, and
• an impeller positioned within the internal volume, the impeller comprising a plurality of blades arranged around a longitudinal axis, the plurality of blades defining an outer circumference,
• wherein the inlet is configured to be placed in the descending aorta and the outlet is configured to be placed in the descending aorta downstream of the inlet,
• wherein the device is configured to have an outflow condition, the outflow condition selected to emulate a vortex in a healthy native descending aorta, and
• wherein the device does not mimic a pulsatile flow imparted by the heart.

A mechanical circulation support device for implantation within a descending aorta in a heart of a patient, the device comprising:

• a mechanical body having an inlet, an outlet, and an internal volume, and
• an impeller positioned within the internal volume, the impeller comprising a plurality of blades arranged around a longitudinal axis, the plurality of blades defining an outer circumference,
• wherein the inlet is configured to be placed in the descending aorta and the outlet is configured to be placed in the descending aorta downstream of the inlet,
• wherein the device is configured to have an outflow condition, the outflow condition selected to emulate a vortex in a healthy native descending aorta, and
• wherein the device is configured to increase renal perfusion without affecting brain flow.