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AssigneeBoston Scientific Scimed, Inc.
InventorsYen-Hao Hsu, Joseph Thomas Delaney, JR., Cristian Parisi, Nicolas Ball-Jones
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In some aspects, the present disclosure pertains to systems for forming crosslinked reaction products that comprises (a) a first composition that comprises a first multifunctional molecule that comprises a plurality of first reactive moieties that comprise azide groups and (b) a second composition that comprises a second multifunctional molecule that comprises a plurality of second reactive moieties that comprise cyclic alkyne groups, where at least one of the first and second multifunctional molecules is a reactive multi-arm polymer and where at least one of the first and second multifunctional molecules comprises an iodinated core. Other aspects of the present disclosure include crosslinked networks formed from such first and second multifunctional molecules and methods of treatment based on crosslinked networks formed from such first and second multifunctional molecules.
A system for forming a crosslinked reaction product comprising (a) a first composition that comprises a first multifunctional molecule that comprises a plurality of first reactive moieties that comprise azide groups and (b) a second composition that comprises a second multifunctional molecule that comprises a plurality of second reactive moieties that comprise cyclic alkyne groups, wherein at least one of the first and second multifunctional molecules is a reactive multi-arm polymer and wherein at least one of the first and second multifunctional molecules comprises an iodinated core.
A crosslinked network formed by combining (a) a first multifunctional molecule that comprises a plurality of first reactive moieties that comprise azide groups and (b) a second multifunctional molecule that comprises a plurality of second reactive moieties that comprise cyclic alkyne groups, wherein at least one of the first and second multifunctional molecules is a reactive multi-arm polymer and wherein at least one of the first and second multifunctional molecules comprises an iodinated core.
A method of treatment comprising administering to a subject a mixture that comprises (a) a first multifunctional molecule that comprises a plurality of first reactive moieties that comprise azide groups and (b) a second multifunctional molecule that comprises a plurality of second reactive moieties that comprise cyclic alkyne groups, wherein at least one of the first and second multifunctional molecules is a reactive multi-arm polymer and wherein at least one of the first and second multifunctional molecules comprises an iodinated core.
Dependencies are inferred from the claim text.