Composition for prevention or treatment of neuroinflammation, containing daphne genkwa flower bud extract as active ingredient
AssigneesUniversity-Industry Cooperation Group of Kyung Hee University, Catholic Kwandong University Industry Foundation
InventorsIk-Hyun CHO, Gyun Jee SONG
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Abstract
The present disclosure relates to a composition for prevention or treatment of neuroinflammation, comprising a Daphne genkwa flower bud extract as an active ingredient. According to the present disclosure, the Daphne genkwa flower bud extract of the present disclosure exhibits anti-inflammatory activity in nerve cells and thus has an effect of inhibiting neuroinflammation, inhibits (hyper) activation of microglia, and prevents neuronal loss and promotes the proliferation of nerve cells, thereby protecting nerves, and thus may be used for the use of reducing neuroinflammatory disease, neurodegenerative disease, or microglial activation.
Claims16
A method for preventing or treating a neuroinflammatory disease, comprising administering to a subject in need thereof a pharmaceutical composition comprising a Daphne genkwa flower bud extract as an active ingredient.
A method for prevention or treatment of neurodegenerative disease, comprising administering to a subject in need thereof a Daphne genkwa flower bud extract as an active ingredient.
A method for reducing activity of microglia in a neurodegenerative disease, comprising administering to a subject in need thereof a Daphne genkwa flower bud extract as an active ingredient.
(canceled)
Dependencies are inferred from the claim text.