Hemofiltration Device and Methods of Use Thereof
AssigneeThe Regents of the University of California
InventorShuvo Roy
Life of this patent
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Abstract
Parallel plate devices for hemofiltration or hemodialysis are provided. A parallel plate device includes a parallel plate assembly having an aligned stack of stackable plate subunits, each stackable plate subunit having a through channel for blood, where the blood channels are opened up at opposite ends of the parallel plate assembly. The parallel plate assembly is configured to form filtrate/dialysate channels interleaved with the blood channels, adjacent channels being separated by a silicon nanoporous filtration membrane. A blood conduit adaptor is attached to the parallel plate assembly at each of the ends, and is configured to distribute blood to or collect blood from the blood channels. Also provided are systems and methods for using the parallel plate devices.
Claims18
1-42. (canceled)
A stackable plate subunit of a parallel plate device, the stackable plate subunit comprising:
- a frame structure partially defined by a first strut opposite second strut, wherein the first strut comprises a slot extending substantially along the entire length of the first strut and the second strut comprises a slot extending substantially along the entire length of the second strut,
- wherein the frame structure comprises a planar through channel partially bound by:
- a first side of a first silicon nanoporous membrane, and
- a first side of a second silicon nanoporous membrane,
- wherein the first silicon nanoporous membrane and the second silicon nanoporous membrane are positioned in the frame such that the membranes are substantially parallel to each other and in a spaced apart configuration and extend between the first and second struts,
- wherein the slot in the first strut forms an opening at a first end of the through channel and the slot in the second strut forms an opening at a second end of the through channel,
- wherein a planar channel is latently formed along each of a second side of the first silicon nanoporous membrane opposite the first side and a second side of the second silicon nanoporous membrane opposite the first side when the stackable plate subunit is stacked.
Dependencies are inferred from the claim text.