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AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsJoseph M. DeSimone, Cooper Owen Shea, Dan Ilyin, Gunilla B. Jacobson, Jean Won Kwak, Kaiwen Hsiao, Maria T. Dulay, Madison M. Driskill, Micah Lawrence, Netra Rajesh, Olayemi Oluwatosin Ajao
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Aspects of the present disclosure include polymeric structures having one or more polymeric microneedles. Polymeric structures according to certain embodiments exhibit a macrostructural change (e.g., exhibit elastic deformation) in response to an applied stimulus. In some embodiments. polymeric structures include a microarray of polymeric microneedles for delivering an active agent compound to a subject or for collecting a biological fluid sample from a subject. Methods for applying a polymeric structure having polymeric microneedles to a skin surface of a subject is also described. Methods for making the polymeric structures, such as by high resolution continuous liquid interface production is also provided. Kits having one or more of the subject polymeric structures are also described.
A polymeric structure comprising one or more polymeric microneedles, wherein the polymeric structure is configured to exhibit a macrostructural change in response to an applied stimulus.
A method comprising applying to a skin surface of a subject a polymeric structure comprising one or more polymeric microneedles, wherein the polymeric structure is configured to exhibit a macrostructural change in response to an applied stimulus.
A method of making a polymeric structure comprising one or more polymeric microneedles that is configured to exhibit a macrostructural change in response to an applied stimulus, the method comprising:
Dependencies are inferred from the claim text.