Gamma-hydroxybutyrate delivering compounds and processes for making and using them
AssigneeZevra Therapeutics, Inc.
InventorsSanjib BERA, Sven GUENTHER, Adam SMITH, Travis MICKLE
Life of this patent
Estimating the term…
Abstract
Disclosed are one or more compounds comprising chemically modified gamma-hydroxybutyrate (GHB), 2-hydroxytetrahydrofuran, and/or 1,4-butanediol, and salts of such compounds (GHB delivering compounds and salts thereof). Also disclosed are compositions comprising at least one GHB delivering compound, or a salt thereof, methods of making such compounds, and methods of using such GHB delivering compounds and compositions. Methods of treatment using the compounds are also disclosed.
Claims24
A method of preventing or treating a sleep disorder or sleep syndrome in a subject in need thereof, the method comprising:
- administering to the subject a composition comprising a therapeutically effective amount of a compound selected from the group consisting of
- or a pharmaceutically acceptable salt thereof.
A method of preventing or treating a sleep disorder or sleep syndrome in a subject in need thereof, the method comprising:
- administering to the subject a composition comprising a therapeutically effective amount of a compound selected from the group consisting of
- or a pharmaceutically acceptable salt thereof;
- and
- an additionally therapeutically effective amount of gamma-hydroxybutyrate or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.