Liquid-liquid phase separation (llps)-based compartments comprising a short peptide and an anionic polymer
AssigneeRamot at Tel-Aviv University Ltd.
InventorsAyala LAMPEL, Itai KATZIR
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Abstract
The present invention provides a composition comprising liquid-liquid phase separation (LLPS)-based compartments comprising a cationic peptide and an anionic polymer, variations and modifications thereof, methods for preparation of the LLPS-based compartments, and uses thereof for delivery or for controlling entrapping and releasing of a payload.
Claims21
-44. (canceled)
A composition comprising a liquid-liquid phase separation (LLPS)-based compartment comprising a cationic peptide and an anionic polymer.
A method of preparing a liquid-liquid phase separation (LLPS)-based compartment, the method comprising mixing a cationic cationic peptide, an anionic polymer, and optionally a payload, wherein the cationic peptide comprises at least one aromatic amino acid, or at least one amino acid modified by a hydrophobic and/or an aromatic cleavable group.
Dependencies are inferred from the claim text.