A computer-implemented method for generating at least one differential marker of the presence of a skin singularity of a human body, said method comprising:
- receiving at a first date of at least a first image of all or part of the human body, forming a first part, of a first individual for displaying a dermoscopic image extracted from said first image with dermoscopic resolution, said first image comprising a plurality of cutaneous singularities of the skin of said body, each singularity having coordinates in a first reference frame associated with said first image and being associated with a first date and at least a first value of a first descriptor, each singularity located in the first image defining a node of a first graph, each node comprising attributes including a position of the singularity and at least one value of a descriptor;
- receiving at a second date of at least one second image of the same first part of the human body of the first individual with substantially identical resolution, said second image comprising a plurality of skin singularities of the skin of said body, each singularity having coordinates in a second reference frame associated with said second image and being associated with a second date and at least one second value of the first descriptor, each singularity located in the second image defining a node of a second graph, each node comprising attributes including a position of the singularity and at least one value of a descriptor;
- generating a first representation comprising the first image and at least one first symbol associated with a first singularity located at a first position of said first image of the first reference frame, said at least first symbol being superimposed on the first image at the first position, said first symbol having a first geometry and/or a first color generated as a function of at least the first value of the first descriptor considered at the first date;
- generating of a second representation in the vicinity of the first representation comprising the second image and at least one second symbol associated with the first singularity, said second symbol having a second geometry and/or a second color, said at least one second symbol being superimposed on the second image at the first position, said second geometry and/or said second color being different from the first geometry and/or the first color thus defining a differential marker, when the calculated distance between a first value of the first descriptor calculated at the first date and a second value of the first descriptor calculated at the second date is greater than a predefined threshold,
- the two images of each representation being oriented and aligned with each other by means of a step of comparing the two graphs and minimizing the error in the positional deviation of the nodes from each other.