Monoclonal antibodies for detecting kawasaki disease antigens

An isolated antibody or antigen binding fragment thereof comprising:

• a heavy chain variable domain comprising:
• a CDRH1 region selected from the group consisting of SEQ ID NOs:
• 2, 14, 22, 30, 42, 50, 62, 78, 86, 93, 101, 123, 126, 139, 149, 152, 164, 176, 186, and 205;
• a CDRH2 region selected from the group consisting of SEQ ID NOs:
• 74, 15, 23, 31, 35, 43, 51, 63, 70, 75, 79, 87, 94, 102, 111, 114, 127, 136, 140, 153, 165, 168, 177, 183, 187, 193, 206, and 212;
• a CDRH3 region selected from the group consisting of SEQ ID NOs:
• 4, 16, 14, 32, 36, 44, 52, 64, 71, 76, 80, 88, 95, 103, 112, 115, 124, 128, 137, 141, 150, 154, 166, 169, 178, 184, 188, 194, 207, 210, and 213;
• and
• a light chain variable domain comprising:
• a CDRL1 region selected from the group consisting of SEQ ID NOs:
• 6, 10, 18, 26, 37, 46, 54, 58, 66, 38, 82, 97, 105, 46, 119, 129, 132, 143, 146, 156, 160, 171, 180, 190, 197, 201, and 215;
• a CDRL2 region selected from the group consisting of SEQ ID NOs:
• 7, 11, 27, 28, 47, 55, 59, 67, 39, 83, 98, 106, 120, 133, 157, 161, 198, 202, and 208;
• and
• a CDRL3 region selected from the group consisting of SEQ ID NOs:
• 8, 12, 20, 28, 39, 48, 56, 60, 68, 73, 84, 99, 107, 109, 117, 121, 130, 134, 144, 147, 158, 162, 172, 174, 181, 191, 199, 203, and 216.