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US 2025/0170237 A1Published application
Muramyl dipeptides and process for preparation thereof
OwnerHalmuthur Mahabalarao Sampath KUMAR, Bonam Srinivasa REDDY +2inventors
InventorsHalmuthur Mahabalarao Sampath KUMAR, Bonam Srinivasa REDDY, Paturu Rama Subba REDDY, Atla SANDEEP
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Abstract
The present invention relates to Muramyl dipeptide compounds having adjuvant activity. The present invention also discloses the process for the preparation of Muramyl dipeptide compound and their intermediates. The immuno-modulating properties of the Muramyl dipeptide compound and their use as NOD2 agonistic adjuvants in vaccine formulations is also disclosed.
Claims11
1-10. (canceled)
A muramyl dipeptide compound according to general formula (I):
- where:
- R1 is selected from substituted or unsubstituted (C3-C6)cycloalkyl, 3 to 6 membered heterocycloalkyl with one or more hetero atoms selected from nitrogen and oxygen, or
- and
- R2 is a C1 to C18 aliphatic chain.
1 more element
Dependencies are inferred from the claim text.