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US 2025/0170232 A1Published application
Vaccines for Neisseria Gonorrhoeae
AssigneeGlaxosmithkline Biologicals SA
InventorsMariagrazia PIZZA, Marzia Monica GIULIANI, Elisabetta MONACI
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Abstract
Methods and compositions for immunizing a human subject against Neisseria gonorrhoeae.
Claims22
A method for immunizing a human subject against Neisseria gonorrhoeae by administering an immunogenic composition comprising an immunologically effective amount of at least one protein antigen, where said protein antigen is selected from:
- (i) a neisserial Heparin Binding Antigen (NHBA);
- (ii) a neisserial factor H binding protein (fHbp) antigen;
- (iii) a neisserial Adhesin A (NadA) antigen;
- (iv) a neisserial GNA1030 antigen;
- and
- (v) a neisserial GNA2091 antigen.
3 more elements
2-24. (canceled)
An immunogenic composition comprising gonococcal OMVs and an adjuvant.
26-28. (canceled)
An immunogenic composition for immunizing a subject in need thereof against Neisseria gonorrhoeae, wherein the immunogenic composition comprises:
- (i) a neisserial Heparin Binding Antigen (NHBA) antigen;
- and
- (ii) a conjugated capsular saccharide from one or more of meningococcal serogroups A, C, W135 and/or Y.
Dependencies are inferred from the claim text.