Method of operating a bioprocess arrangement to perform at least one repetition of a bioprocess

A method of operating a bioprocess arrangement to perform at least one repetition of a bioprocess, wherein the bioprocess arrangement comprises physical components for performing the bioprocess, wherein the physical components comprise at least one replaceable electronic component, wherein the bioprocess arrangement comprises a process control system, wherein the process control system controls the bioprocess arrangement,

• wherein the process control system uses a digital model of the bioprocess arrangement for controlling the bioprocess arrangement, wherein the digital model comprises digital representations of the replaceable electronic components, wherein the process control system communicates with the replaceable electronic components to perform the bioprocess by controlling the bioprocess arrangement based on the digital model,
• wherein the replaceable electronic components are removed during the bioprocess and/or between repetitions of the bioprocess and replaced by new electronic components, that the process control system automatically detects the removal of the replaceable electronic components, that the process control system automatically detects the presence of the new electronic components, that the process control system communicates with the new electronic components, that the process control system retrieves digital representations of the new electronic components based on the communication with the new electronic components, that the process control system derives from the digital representations of the replaceable electronic components and the new electronic components a functional relationship between the replaceable electronic components and the new electronic components, that the process control system replaces the digital representations of the replaceable electronic components with the digital representations of the new electronic components based on the functional relationship thereby updating the digital model, and, that the process control system controls the bioprocess arrangement to perform the bioprocess based on the updated digital model.