Improved cell lines and methods for the production of adeno-associated vectors
AssigneeCevec Pharmaceuticals GmbH
InventorsMichelle Hussong, Tobias Bonifert, Helmut Kewes
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Abstract
The present invention relates to cell lines in which DNA fragmentation is inhibited, uses of cell lines in which DNA fragmentation is inhibited for the production of Adeno-associated virus (AAV), related methods of producing AAV, and methods of producing AAV, comprising the step of exposing the cells in which AAV is produced to an inhibitor of DNA fragmentation during the AAV production phase.
Claims20
A cell line in which DNA fragmentation is inhibited.
Use of a cell line in which DNA fragmentation is inhibited for the production of Adeno-associated virus (AAV).
A method of producing Adeno-associated virus (AAV), comprising the step of exposing the cells in which AAV is produced to an inhibitor of DNA fragmentation during the AAV production phase.
Dependencies are inferred from the claim text.