Phentolamine mesylate and therapeutic uses thereof
AssigneeOpus Genetics, Inc.
InventorsDaniela Carmen Oniciu, Rosa Maria Espinosa Ferrer
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Abstract
This invention provides phentolamine mesylate that exhibits a particular x-ray powder diffraction (XRPD) pattern or exhibits one or more particular XRPD peaks. The invention also provides compositions comprising the phentolamine mesylate and compositions in which the phentolamine mesylate is dissolved. The invention also provides methods for treating or preventing an ocular disease or condition, comprising administering to a subject in need thereof an effective amount of the phentolamine mesylate, a composition comprising the phentolamine mesylate or a composition in which the phentolamine mesylate is dissolved.
Claims46
Phentolamine mesylate that exhibits an X-ray powder diffraction (XRPD) pattern comprising a peak at 8.4±0.2 degrees 2-theta, a peak at 13.1±0.2 degrees 2-theta, a peak at 16.3±0.2 degrees 2-theta, a peak at 19.4±0.2 degrees 2-theta, and a peak at 20.8±0.2 degrees 2-theta.
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Phentolamine mesylate that exhibits an XRPD pattern that is substantially the same as that depicted in FIG. 2A.
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Dependencies are inferred from the claim text.