Negative pressure laser handpiece

A method for treatment of a skin neoplasm of skin of a subject, the method comprising:

• (a) providing a chamber having an end wall, a side wall extending away from the end wall, and an opening opposite the end wall, wherein the end wall, the side wall and the opening define an interior space of the chamber, wherein the side wall terminates in a contact surface for sealing against skin of a subject, wherein the contact surface defines the opening;
• (b) positioning the contact surface of the chamber on the skin of the subject such that the contact surface surrounds the skin neoplasm and the contact surface seals against the skin of the subject;
• (c) creating negative pressure in the interior space of the chamber;
• and
• (d) irradiating the skin neoplasm with light from a light source selected from the group consisting of laser light sources and wavelength-filtered light sources.

A method for treatment of a skin malformation of skin of a subject, the method comprising:

• (a) providing a chamber having an end wall, a side wall extending away from the end wall, and an opening opposite the end wall, wherein the end wall, the side wall and the opening define an interior space of the chamber, wherein the side wall terminates in a contact surface for sealing against skin of a subject, wherein the contact surface defines the opening;
• (b) positioning the contact surface of the chamber on the skin of the subject such that the contact surface surrounds the skin malformation and the contact surface seals against the skin of the subject;
• (c) creating negative pressure in the interior space of the chamber;
• and
• (d) irradiating the skin malformation with light from a light source selected from the group consisting of laser light sources and wavelength-filtered light sources.