Electroporation probe with selectable injection rates and selectable electric field strength
AssigneeRadioclash Inc.
InventorsSamit Dharia, Duane Bester
Life of this patent
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AssigneeRadioclash Inc.
InventorsSamit Dharia, Duane Bester
Estimating the term…
An improved electroporation probe that delivers both electroporation and medicinal solution injection via a single instrument, and which allows altering of the applied electric field based on requirements of the target, is disclosed. A proximal end of a hollow tubular probe is connected to an injector for injecting medications, cells, proteins or biologics in solution into the probe, and which in turn are ejected through unsealed perforations on a perforated portion of the probe towards its distal end. A movable sleeve is slidable over the perforated portion of the probe in order to seal or unseal its perforations. A tapered metallic tip at the distal end of the probe is connected to an anode terminal of a battery, the distal end of the movable sleeve is connected to a cathode terminal of the battery. Separation between the tip and the distal end of the movable sleeve is varied to generate desired strength of the electric field needed for electroporation of target cells, or to selectively unseal more or fewer perforations for medicinal solution delivery at the target.
An electroporation probe comprising:
A method of providing electroporation and a medicinal solution at a target site, said method comprising:
Dependencies are inferred from the claim text.