# US 2025/0155697 A1 · Biological fluid analyser with adaptive light source assembly > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2025/0155697 A1 - Document ID: US20250155697A1 - Status: Published application - Kind: A1 - Application number: 18/722,185 - Filed: 2022-12-22 - Published: 2025-05-15 - Earliest claimed: 2021-12-23 - Assignees: Radiometer Medical ApS - Applicants: Radiometer Medical ApS - Inventors: Peter Emil LARSEN; Thomas Steen HANSEN; Mohammad Esmail ARYAEE PANAH - Web page: https://patentgrep.com/patent/US20250155697A1 ## CPC - G02B 21/082: {for incident illumination only} - G02B 21/361: {Optical details, e.g. image relay to the camera or image sensor (G02B21/364 takes precedence; illumination details G02B21/06 and subgroups)} - G01N 15/1434: Optical arrangements - G02B 21/365: {Control or image processing arrangements for digital or video microscopes (G02B21/361, G02B21/362 take precedence)} - G01N 2015/1006: {for cytology} - G01N 2015/144: {Imaging characterised by its optical setup} - G02B 19/0066: {in the form of an LED array} - G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) ## Abstract A biological fluid analyser is provided, the biological fluid analyser comprising an imaging system comprising a light source assembly configured to emit light; a first lens assembly configured to direct the light from the light source assembly to directly or indirectly define a probing light; the imaging system defining a probing volume configured to receive probing light and configured to receive a container comprising a prepared biological fluid sample; the biological fluid analyser comprising a controller configured to control the light source assembly according to a light configuration, wherein the light source assembly, in response to a first light control signal, is configured to emit light according to a first light configuration, and wherein the light source assembly, in response to a second light control signal, is configured to emit light according to a second light configuration. ## Claims ### Claim 1 A biological fluid analyzer comprising: an imaging system comprising: a light source assembly configured to emit light, a first lens assembly configured to direct the light from the light source assembly to directly or indirectly define a probing light, and the imaging system defining a probing volume configured to receive the probing light and configured to receive a container comprising a prepared biological fluid sample; and a controller configured to control the light source assembly according to a light configuration, wherein the light source assembly, in response to a first light control signal, is configured to emit light according to a first light configuration, and wherein the light source assembly, in response to a second light control signal, is configured to emit light according to a second light configuration. ### Claim 2 (depends on 1) The biological fluid analyzer according to claim 1, wherein the imaging system comprises an aperture device configured to apply an aperture to allow light from the first lens assembly to pass through the aperture, and wherein the imaging system further comprises a second lens assembly configured to direct light from the aperture device. ### Claim 3 (depends on 1) The biological fluid analyzer according to claim 1, wherein the biological fluid analyzer comprises a container configured to contain a prepared biological fluid sample, and wherein the container is arranged in the probing volume. ### Claim 4 (depends on 1) The biological fluid analyzer according to claim 1, wherein the first light configuration comprises a first light pattern, and wherein the light source assembly, in response to the first light control signal, is configured to emit light with the first light pattern. ### Claim 5 (depends on 4) The biological fluid analyzer according to claim 4, wherein the second light configuration comprises a second light pattern, and wherein the light source assembly, in response to the second light control signal, is configured to emit light with the second light pattern. ### Claim 6 (depends on 5) The biological fluid analyzer according to claim 5, wherein the light source assembly comprises an array of light sources; wherein, in response to the first light control signal, the array of light sources is configured to emit light according to a first geometrical pattern corresponding to the first light pattern; and wherein, in response to the second light control signal, the array of light sources is configured to emit light according to a second geometrical pattern corresponding to the second light pattern. ### Claim 7 (depends on 1) The biological fluid analyzer according to claim 1, wherein the light source assembly comprises a glass substrate comprising a liquid crystal display, and wherein the light source assembly, in response to the first light control signal, is configured to apply a first transparency pattern in the glass substrate for emitting light with the first light configuration, and wherein the light source assembly, in response to the second light control signal, is configured to apply a second transparency pattern in the glass substrate for emitting light with the second light configuration. ### Claim 8 (depends on 1) The biological fluid analyzer according to claim 1, wherein the first light configuration comprises a first color scheme, and wherein the light source assembly, in response to the first light control signal, is configured to emit light having the first color scheme, and wherein the second light configuration comprises a second color scheme, and wherein the light source assembly, in response to the second light control signal, is configured to emit light having the second color scheme. ### Claim 9 (depends on 1) The biological fluid analyzer according to claim 1, wherein the first light configuration comprises a first intensity scheme, and wherein the light source assembly, in response to the first light control signal, is configured to emit light having the first intensity scheme. ### Claim 10 (depends on 1) The biological fluid analyzer according to claim 1, wherein the second light configuration comprises a second intensity scheme, and wherein the light source assembly, in response to the second light control signal, is configured to emit light having the second intensity scheme. ### Claim 11 (depends on 1) The biological fluid analyzer according to claim 1, wherein the light source assembly, in response to a third light control signal from the controller, is configured to emit light according to a third light configuration. ### Claim 12 (depends on 1) The biological fluid analyzer according to claim 1, wherein the light source assembly, in response to one or more of the first and the second light control signals, is configured to emit light decentred from an optical axis of the imaging system. ### Claim 13 (depends on 1) The biological fluid analyzer according to claim 1, wherein the imaging system comprises a third lens assembly configured to direct light from the probing volume and a light sensor configured to receive light directed by the third lens assembly.