Systems For Cell Culture Scaling

A scalable bioreactor system for transitioning from testing to commercial production, comprising:

• a first bioreactor, comprising:
• a first bioprocessing container having a first end, a second end, and a sidewall;
• a first configurable mixing assembly suspended between the first and second ends of the first bioprocessing container;
• and
• a first impeller having a first diameter, the first impeller attached to the first configurable mixing assembly in a first position, wherein the first diameter and the first position are selected to achieve a set of operational parameters;
• a second bioreactor, comprising
• a second bioprocessing container having a first end, a second end, and a sidewall, wherein the second bioprocessing container is not the same volume as the first bioprocessing container;
• a second configurable mixing assembly suspended between the first and second ends of the second bioprocessing container;
• and
• a second impeller having a second diameter that is not the same as the first diameter, the second impeller attached to the second configurable mixing assembly in a second position, wherein the second diameter and the second position are selected to match the set of operational parameters and the operational parameters include power per volume and impeller tip speed.