Safe injection systems and methods

A system for injection, comprising:

• a syringe body having a syringe body proximal end and a syringe body distal end, and defining a syringe body interior therebetween;
• a needle hub assembly coupled to the syringe body at the syringe body distal end, and comprising
• a needle hub, and
• a needle removably coupled to the needle hub and having a sharp needle distal end and a needle proximal end feature;
• a stopper member movably disposed in the syringe interior;
• a plunger member having a plunger member proximal end and a plunger member distal end;
• and
• a needle retention member releasably coupled to the plunger member and configured to couple to the needle proximal end feature,
• wherein the plunger member is configured to insert the stopper member distally in the syringe interior relative to the syringe body and the needle hub, and
• wherein the plunger member and the syringe body are configured such that, when the stopper member is inserted to the syringe body distal end, the needle proximal end pierces the stopper member to couple to the needle retention member and the needle retention member proximal end is disposed in the syringe body interior.

A system for injection, comprising:

• an autoinjector, comprising
• a housing;
• a syringe, comprising
• a syringe body having a syringe body proximal end and a syringe body distal end, and defining a syringe body interior therebetween,
• a needle hub assembly coupled to the syringe body at the syringe body distal end, and comprising
• a needle hub, and
• a needle removably coupled to the needle hub and having a sharp needle distal end and a needle proximal end feature,
• a stopper member movably disposed in the syringe interior, and
• a plunger member having a plunger member proximal end and a plunger member distal end, and coupled to the stopper member at the plunger member distal end,
• wherein the plunger member is configured to insert the stopper member distally in the syringe interior relative to the syringe body and the needle hub, and
• wherein the plunger member and the syringe body are configured such that, when the stopper member is inserted to the syringe body distal end, the plunger member proximal end is flush with the syringe body proximal end or disposed in the syringe body interior.