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US 2025/0152680 A1Published application
Compositions comprising glucocerebrocidase and methods of use thereof
OwnerRobert Russell GOTSCHALL, Lin LIUinventors
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Abstract
Provided are compositions comprising glucocerebrosidase having increased phosphorylation of High Mannose and Hybrid N-linked Oligosaccharides. Also provided herein are methods of treating Gaucher disease comprising administering to a subject the compositions of the disclosure.
Claims15
A composition comprising glucocerebrosidase, wherein at least 50% of the N-linked glycans on glucocerebrosidase are phosphorylated.
Dependencies are inferred from the claim text.