# US 2025/0147005 A1 · Intestinal information estimation system

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 2025/0147005 A1
- Document ID: US20250147005A1
- Status: Published application
- Kind: A1
- Application number: 18/832,868
- Filed: 2023-01-20
- Published: 2025-05-08
- Earliest claimed: 2022-01-27
- Assignees: KYOCERA Corporation
- Applicants: KYOCERA Corporation
- Inventors: Shingo TERANISHI; Daisuke UEYAMA; Shinichi ABE
- Web page: https://patentgrep.com/patent/US20250147005A1

## CPC

- G01N 33/4975: {other than oxygen, carbon dioxide or alcohol, e.g. organic vapours}
- C12M 1/34: Measuring or testing with condition measuring or sensing means, e.g. colony counters
- C12Q 1/04: Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor {(C12Q1/6897 takes precedence)}
- E03D 9/00: Sanitary or other accessories for lavatories (hand tools for cleaning the toilet bowl A47K11/10; seats or covers for closets A47K13/00; body supports, other than seats for closets A47K17/02; devices for preventing contamination of drinking-water pipes E03C1/10 ){; Devices for cleaning or disinfecting the toilet room or the toilet bowl; Devices for eliminating smells (cleaning, disinfecting or deodorising the seat A47K13/30)}
- G01N 33/00: Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N 33/0044: {Sulphides, e.g. H2S}
- G01N 33/497: of gaseous biological material, e.g. breath
- G01N 33/4977: {Metabolic gas from microbes, cell cultures or plant tissues}
- G01N 33/50: Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing (measuring or testing processes involving enzymes or microorganisms, compositions or test papers therefor; processes for forming such compositions, condition responsive control in microbiological or enzymological processes C12Q)
- G01N 33/98: involving alcohol, e.g. ethanol in breath
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- C12M: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; {APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS}
- C12Q: MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- E03D: WATER-CLOSETS OR URINALS WITH FLUSHING DEVICES; FLUSHING VALVES THEREFOR

## Abstract

Intestinal information of a subject is accurately estimated from a component contained in a gas generated from feces of the subject. Included are a detector configured to detect a predetermined component from a gas released from feces of a subject and output a detection signal depending on a concentration of the predetermined component and an estimator configured to input the detection signal or the concentration of the predetermined component corresponding to the detection signal to a prediction model and estimate information regarding an amount and/or an existence ratio of short-chain fatty acid-producing bacteria and/or a metabolite contained in the feces of the subject. The predetermined component is at least one selected from the group consisting of methyl mercaptan, hydrogen sulfide, hydrogen, and carbon dioxide.

## Claims

### Claim 1

An intestinal information estimation system, comprising:
a detector configured to detect a predetermined component from a gas released from feces of a subject and output a detection signal depending on a concentration of the predetermined component; and
an estimator configured to input the detection signal or the concentration of the predetermined component corresponding to the detection signal to a prediction model and estimate information regarding an amount and/or an existence ratio of short-chain fatty acid-producing bacteria and/or a metabolite contained in the feces of the subject,
wherein the predetermined component is at least one selected from the group consisting of methyl mercaptan, hydrogen sulfide, hydrogen, and carbon dioxide.

### Claim 2 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the prediction model is generated by machine learning using learning data including a combination of (1) a detection signal output from the detector when gases each released from a plurality of feces are supplied to the detector or a concentration of the predetermined component corresponding to the detection signal and (2) measurement information obtained by analyzing in advance and including information regarding an amount and/or an existence ratio of short-chain fatty acid-producing bacteria and/or a metabolite contained in each of the plurality of feces.

### Claim 3 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the short-chain fatty acid-producing bacteria are butyric acid-producing bacteria and/or acetic acid-producing bacteria.

### Claim 4 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the metabolite is butyric acid and/or acetic acid.

### Claim 5 (depends on 1)

The intestinal information estimation system according to claim 1, wherein information regarding an amount and/or an existence ratio of Faecalibacteria is estimated from a concentration of methyl mercaptan detected from the gas released from the feces of the subject.

### Claim 6 (depends on 1)

The intestinal information estimation system according to claim 1, wherein information regarding an amount and/or an existence ratio of butyric acid is estimated from a concentration of hydrogen sulfide detected from the gas released from the feces of the subject.

### Claim 7 (depends on 1)

The intestinal information estimation system according to claim 1, wherein information regarding an amount and/or an existence ratio of bifidobacteria is estimated from a concentration of carbon dioxide and/or hydrogen detected from the gas released from the feces of the subject.

### Claim 8 (depends on 1)

The intestinal information estimation system according to claim 1, wherein information regarding an amount and/or an existence ratio of acetic acid is estimated from a concentration of hydrogen detected from the gas released from the feces of the subject.

### Claim 9 (depends on 1)

The intestinal information estimation system according claim 1, wherein information regarding an amount and/or an existence ratio of ornithine is estimated from a concentration of carbon dioxide and/or the methyl mercaptan detected from the gas released from the feces of the subject.

### Claim 10 (depends on 1)

The intestinal information estimation system according to claim 1, wherein information regarding an amount and/or an existence ratio of Coprococcus bacteria is estimated from a concentration of carbon dioxide detected from the gas released from the feces of the subject.

### Claim 11 (depends on 1)

The intestinal information estimation system according to claim 1, wherein information regarding an amount and/or an existence ratio of at least one selected from the group consisting of Streptococcus bacteria, Ruminococcus bacteria, Lachnospira bacteria, and trimethylamine is estimated from a concentration of methyl mercaptan detected from the gas released from the feces of the subject.

### Claim 12 (depends on 1)

The intestinal information estimation system according to claim 1,
wherein the detector can detect 2-propanol from the gas released from the feces of the subject, and
information regarding an amount and/or an existence ratio of Bilophila bacteria is estimated from a concentration of 2-propanol detected from the gas released from the feces of the subject.

### Claim 13 (depends on 1)

The intestinal information estimation system according to claim 1 further comprising
a health information generator configured to generate health information based on an estimation result from the estimator.

### Claim 14 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the detector is installed in a toilet of a bathroom.

### Claim 15 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the detector is installed in a bed for a person requiring nursing care.

### Claim 16 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the detector can be carried by the subject.

### Claim 17 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the estimator inputs the detection signal or a concentration of the predetermined component corresponding to the detection signal to a prediction model depending on a property of the subject.

### Claim 18 (depends on 1)

The intestinal information estimation system according to claim 1, wherein the estimator inputs information regarding a property of the subject to a prediction model.
