# US 2025/0144010 A1 · Guiding Musculoskeletal Procedures

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- Number: US 2025/0144010 A1
- Document ID: US20250144010A1
- Status: Published application
- Kind: A1
- Application number: 18/952,876
- Filed: 2024-11-19
- Published: 2025-05-08
- Earliest claimed: 2020-05-18
- Assignees: Agitated Solutions Inc.
- Applicants: Agitated Solutions Inc.
- Inventors: Morgan Evans; Kenneth Trauner
- Web page: https://patentgrep.com/patent/US20250144010A1

## CPC

- A61K 9/0019: {Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00)}
- A61K 47/02: Inorganic compounds
- A61P 19/02: for joint disorders, e.g. arthritis, arthrosis
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

A method may include providing a syringe device having (a) a single needle, (b) a first syringe comprising saline with microbubbles, (c) a second syringe comprising a therapeutic compound, and (d) a connector coupling the single needle to the first syringe and to the second syringe. The method may further include guiding the single needle to an injection site of a patient; injecting, with the first syringe, a quantity of saline with microbubbles; confirming a desired position of the single needle, with ultrasound imaging, by identifying the microbubbles in the quantity of saline relative to a tip of the single needle and further relative to one or more anatomical landmarks visible with the ultrasound imaging; and injecting, with the second syringe, the therapeutic compound at the injection site.

## Claims

### Claim 1

A method comprising:
providing a syringe device having a single needle, a first syringe comprising saline with microbubbles, a second syringe comprising a therapeutic compound, and a connector coupling the single needle to the first syringe and to the second syringe;
guiding the single needle to an injection site of a patient;
injecting, with the first syringe, a quantity of saline with microbubbles;
confirming a desired position of the single needle, with ultrasound imaging, by identifying the microbubbles in the quantity of saline relative to a tip of the single needle and further relative to one or more anatomical landmarks visible with the ultrasound imaging; and
injecting, with the second syringe, the therapeutic compound at the injection site.

### Claim 2 (depends on 1)

The method of claim 1, wherein the therapeutic compound comprises a corticosteroid.

### Claim 3 (depends on 1)

The method of claim 1, wherein the therapeutic compound comprises lidocaine.

### Claim 4

A method comprising:
providing a syringe device having a single needle, a first syringe comprising saline with microbubbles, a second syringe configured to aspirate fluid from a treatment site of a patient, and a connector coupling the single needle to the first syringe and to the second syringe;
guiding the single needle to the treatment site;
injecting, with the first syringe, a quantity of saline with microbubbles;
confirming a desired position of the single needle, with ultrasound imaging, by identifying the microbubbles in the quantity of saline relative to a tip of the single needle and further relative to one or more anatomical landmarks visible with the ultrasound imaging; and
aspirating, with the second syringe, fluid from the treatment site.

### Claim 5

A method comprising:
providing a syringe device having a single needle, a first syringe comprising saline with microbubbles and having a first-syringe plunger, a second syringe having a second-syringe plunger that is independently operable relative to the first-syringe plunger, and a connector coupling the single needle to the first syringe and to the second syringe;
guiding the single needle to a treatment site of a patient;
injecting, with the first syringe, a quantity of saline with microbubbles;
confirming a desired position of the single needle, with ultrasound imaging, by identifying the microbubbles in the quantity of saline relative to a tip of the single needle and further relative to one or more anatomical landmarks visible with the ultrasound imaging; and
with the second syringe, injecting a therapeutic compound at the treatment site or aspirating fluid from the treatment site.

### Claim 6 (depends on 5)

The method of claim 5, wherein injecting with the first syringe comprises depressing the first-syringe plunger.

### Claim 7 (depends on 5)

The method of claim 5, wherein the second syringe comprises the therapeutic compound, and wherein injecting the therapeutic compound comprises depressing the second-syringe plunger.

### Claim 8 (depends on 5)

The method of claim 5, wherein the second syringe is configured to aspirate fluid from a treatment site of a patient, and wherein aspirating fluid from the treatment site comprises drawing back the second-syringe plunger.
