# US 2025/0143989 A1 · Teeth whitening composition with vitamins

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- Number: US 2025/0143989 A1
- Document ID: US20250143989A1
- Status: Published application
- Kind: A1
- Application number: 18/727,893
- Filed: 2023-01-09
- Published: 2025-05-08
- Earliest claimed: 2022-01-13
- Assignees: Ids Research Societa' A Responsabilita' Limitata
- Applicants: Ids Research Societa' A Responsabilita' Limitata
- Inventors: Remigio PIERGALLINI; Nikolaos LOUPIS
- Web page: https://patentgrep.com/patent/US20250143989A1

## CPC

- A61K 8/38: Percompounds, e.g. peracids
- A61K 8/0208: {Tissues; Wipes; Patches}
- A61K 8/042: {Gels}
- A61K 8/24: Phosphorous; Compounds thereof
- A61K 8/44: Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K 8/67: Vitamins
- A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61K 2800/522: Antioxidants; Radical scavengers
- A61K 2800/882: Mixing prior to application
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A teeth whitening composition comprising a first gel comprising a peroxide, and a second gel comprising vitamin K, vitamin D, and hydroxyapatite, wherein said hydroxyapatite of the second gel is a ground hydroxyapatite with nanometric particles and wherein the two gels are mixed together to obtain the final composition.

## Claims

### Claim 1

Teeth whitening composition comprising:
a first gel comprising a peroxide, and
a second gel comprising vitamin K, vitamin D, and hydroxyapatite; wherein said hydroxyapatite of the second gel is a ground hydroxyapatite with nanometric particles,
wherein the two gels are mixed together to obtain the final composition.

### Claim 2 (depends on 1)

The composition according to claim 1, wherein the first gel comprises a pH regulator in order to have a pH lower than or equal to 5, preferably comprised between 4.5 and 5.

### Claim 3 (depends on 2)

The composition according to claim 2, wherein said pH regulator of the first gel comprises ethylenediaminetetraacetic acid (EDTA), disodium hydrogen phosphate (Na2HPO4) and/or sodium hydroxide (NaOH).

### Claim 4 (depends on 1)

The composition according to claim 1, wherein the second gel comprises a pH regulator in order to have a pH higher than 6, preferably comprised between 6.5 and 7.

### Claim 5 (depends on 4)

The composition according to claim 4, wherein said pH regulator of the second gel comprises ethylenediaminetetraacetic acid (EDTA), disodium hydrogen phosphate (Na2HPO4) and/or sodium hydroxide (NaOH).

### Claim 6 (depends on 1)

The composition according to claim 1, wherein said vitamin D of the second gel comprises vitamin D3 (cholecalciferol) and/or vitamin D2 (ergocalciferol).

### Claim 7 (depends on 1)

The composition according to claim 1, wherein said vitamin K of the second gel comprises vitamin K2 (menaquinone of bacterial origin), and/or vitamin K3 (water-soluble menadione of synthetic origin).

### Claim 8 (depends on 1)

The composition according to claim 1, wherein said peroxide of the first gel comprises carbamide peroxide.

### Claim 9 (depends on 1)

The composition according to claim 1, wherein in said final composition the peroxide has a weight percentage comprised between 6% and 8% relative to the weight of the final composition.

### Claim 10 (depends on 1)

The composition according to claim 1, wherein in said final composition:
the vitamin K has a weight percentage comprised between 0.25 and 0.35 relative to the weight of the final composition;
the vitamin D has a weight percentage comprised between 0.25 and 0.35 relative to the weight of the final composition; and
the hydroxyapatite has a weight percentage comprised between 0.7 and 0.9 relative to the weight of the final composition.