Electroporation for obesity or diabetes treatment
AssigneeMayo Foundation for Medical Education and Research
InventorsChristopher V. DESIMONE, Barham K. ABU DAYYEH, Samuel J. ASIRVATHAM
Life of this patent
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Abstract
Endolumenal devices and methods can be used for the treatment of health conditions including obesity and diabetes. In some embodiments, the methods and systems provided herein can cause weight loss or control diabetes by reducing the caloric absorption of an individual. For example, this document provides several devices and methods for treating obesity and diabetes by using electroporation to modulate the duodenal mucosa. In addition, this document provides devices and methods for bypassing portions of the gastrointestinal tract to reduce nutritional uptake.
Claims31
-29. (canceled)
A method of treating diabetes in a patient, comprising:
- advancing an electroporation device comprising one or more electrodes into a duodenum of the patient;
- and
- delivering electroporation energy to mucosa of the duodenum using the one or more electrodes to treat diabetes, wherein the electroporation energy reshapes the mucosa of the duodenum.
A method of treating diabetes in a patient, comprising:
- advancing an electroporation device comprising one or more electrodes into a duodenum of the patient;
- and
- delivering electroporation energy to mucosa of the duodenum using the one or more electrodes to treat diabetes, wherein the electroporation energy resets diseased mucosa of the duodenum.
A method of treating diabetes in a patient, comprising:
- advancing an electroporation device comprising one or more electrodes into a duodenum of the patient;
- transitioning the electroporation device from a first configuration to a second configuration, wherein transitioning the electroporation device to the second configuration stretches at least a portion of the duodenum;
- and
- delivering electroporation energy to mucosa of the duodenum using the one or more electrodes to treat diabetes.
A method of treating diabetes in a patient, comprising:
- advancing an electroporation device comprising one or more electrodes into a duodenum of the patient, wherein the electroporation device comprises a rolled-up member comprising the one or more electrodes;
- and
- delivering electroporation energy to mucosa of the duodenum using the one or more electrodes to treat diabetes.
Dependencies are inferred from the claim text.