# US 2025/0143684 A1 · Biocompatible biomedical occlusion device

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- Number: US 2025/0143684 A1
- Document ID: US20250143684A1
- Status: Published application
- Kind: A1
- Application number: 19/018,495
- Filed: 2025-01-13
- Published: 2025-05-08
- Earliest claimed: 2015-04-23
- Assignees: The Texas A&M University System
- Applicants: The Texas A&M University System
- Inventors: Mark Wierzbicki; Duncan Maitland; Matthew W. Miller; Andrea D. Muschenborn; Landon Nash; Jason M. Szafron; Todd Landsman
- Web page: https://patentgrep.com/patent/US20250143684A1

## CPC

- A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)}
- A61B 17/12031: {complete occlusion}
- A61B 2017/00243: {cardiac}
- A61B 2017/00575: {for closure at remote site, e.g. closing atrial septum defects}
- A61B 2017/00592: {Elastic or resilient implements}
- A61B 2017/00606: {Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening}
- A61B 2017/00867: {shape memory effect}
- A61B 2017/00871: {polymeric}
- A61L 31/146: {Porous materials, e.g. foams or sponges}
- A61L 2400/16: Materials with shape-memory or superelastic properties
- A61L 2430/36: for embolization or occlusion, e.g. vaso-occlusive compositions or devices
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.

## Claims

### Claim 1

A method for creating a device for a tissue channel, comprising:
creating a plurality of slots in one or more elastic tubes;
shape setting the one or more elastic tubes to a preconfigured shape to form a device frame having a proximal structure, a distal structure, and an intermediate structure, wherein the proximal structure and distal structure each have a larger diameter than the intermediate structure;
configuring an attachment structure to the device frame; and
coupling a shape memory polymer foam segment to the device frame.

### Claim 2

A system comprising:
a conduit comprising: (a)(i) a proximal portion including proximal struts, (a)(ii) a distal portion including distal struts, and (a)(iii) a middle portion coupling the proximal struts to the distal struts; and
a shape memory polymer (SMP) foam that expands from an unactuated configuration to an actuated configuration;
wherein (b)(i) the proximal and distal struts include a shape memory (SM) material, (b)(ii) the proximal struts expand from a first proximal configuration to a second proximal configuration and the distal struts expand from a first distal configuration to a second distal configuration, (b)(iii) the second proximal configuration has a larger maximum outer diameter than the first proximal configuration and the second distal configuration has a larger maximum outer diameter than the first distal configuration, and (b)(iv) the SMP foam is, in the unactuated configuration, included within the proximal struts when the proximal struts are in the second proximal configuration.