Methods for producing cmv vectors
AssigneeVir Biotechnology, Inc.
InventorsSarah Ledoux, Eric Bruening, Janet L. Douglas, Christine R. Meyer
Life of this patent
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Abstract
The present disclosure provides methods for producing cytomegalovirus (CMV) viral vectors. The present disclosure also provides methods for modifying host cells for use in producing CMV viral vectors.
Claims45
A method of producing a progeny cytomegalovirus (CMV), comprising:
- (a) introducing to a cell a mRNA molecule encoding a gene that is essential for or augments CMV replication;
- (b) infecting the cell with a parent CMV;
- (c) incubating the cell;
- and
- (d) collecting the progeny CMV.
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A mRNA molecule comprising the nucleotide sequence of SEQ ID NO:
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A mRNA molecule comprising the nucleotide sequence of SEQ ID NO:
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Dependencies are inferred from the claim text.