Cancer vaccine comprising epitope of c-met and use thereof
AssigneeKorea University Research and Business Foundation
InventorKyong Hwa PARK
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Abstract
The present invention has been completed by identifying an epitope of a c-Met protein which functions as a tumor antigen, and relates to the use of an epitope peptide as a cancer vaccine, and the like. The epitope peptide of c-Met according to the present invention is a cancer vaccine for suppressing cancer progression and preventing cancer metastasis by inducing the activation of antigen-specific T1 cells, and can be administered in combination with an immune checkpoint inhibitor.
Claims7
A peptide consisting of an amino acid sequence of SEQ ID NO:
- 5 or 6.
A cancer vaccine composition comprising a c-Met-derived peptide as an active ingredient,
- wherein the peptide comprises an amino acid sequence of SEQ ID NO:
- 5 and/or 6.
A pharmaceutical composition for preventing or treating cancer comprising a c-Met-derived peptide as an active ingredient,
- wherein the peptide comprises an amino acid sequence of SEQ ID NO:
- 5 and/or 6.
Dependencies are inferred from the claim text.