# US 2025/0132013 A1 · Systems, methods, and devices for custom sleep age implementation

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- Number: US 2025/0132013 A1
- Document ID: US20250132013A1
- Status: Published application
- Kind: A1
- Application number: 18/999,439
- Filed: 2024-12-23
- Published: 2025-04-24
- Earliest claimed: 2020-08-21
- Assignees: StimScience Inc.
- Applicants: StimScience Inc.
- Inventors: Ram Gurumoorthy
- Web page: https://patentgrep.com/patent/US20250132013A1

## CPC

- A61B 5/4812: {Detecting sleep stages or cycles}
- G16H 20/40: relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
- A61B 5/4815: {Sleep quality}
- A61B 5/4836: {Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence)}
- G16H 20/30: relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- G16H 50/30: for calculating health indices; for individual health risk assessment
- G16H 50/50: for simulation or modelling of medical disorders
- A61B 5/4806: {Sleep evaluation (A61B5/4821 takes precedence; devices for inducing sleep A61M21/02)}
- A61B 5/7475: {User input or interface means, e.g. keyboard, pointing device, joystick}
- A61M 21/02: for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia (for massage A61H; electrotherapy A61N, e.g. applying alternating or intermittent electric currents for producing anaesthesia A61N1/36021)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

Provided are systems, methods, and devices for implementation of custom sleep age profiles. Methods include generating at least one sleep model based, at least in part, on reference data, the at least one sleep model being configured to identify an estimated sleep age based on an input. Methods further include receiving measurement data comprising data values representing measurements of neural activity of at least one user, and generating an estimated sleep age of the at least one user based, at least in part, on the at least one sleep model and the received measurement data. Methods also include generating a plurality of stimulation parameters based, at least in part, on the estimated sleep age, the plurality of stimulation parameters being configured to modify the estimated sleep age of the at least one user.

## Claims

### Claim 1

A method comprising:
generating, using one or more processors, at least one wake model based, at least in part, on reference data, the at least one wake model being configured to identify an estimated wake age of at least one user based on a measurement data;
receiving the measurement data comprising data values representing measurements of neural activity of the at least one user;
generating, using the one or more processors, the estimated wake age of the at least one user based, at least in part, on the at least one wake model and the received measurement data;
generating, using the one or more processors, at least one stimulation parameter based, at least in part, on the estimated wake age, the at least one stimulation parameter being configured to modify the estimated wake age of the at least one user; and
applying a stimulus to a brain of the at least one user based on the at least one stimulation parameter.

### Claim 2 (depends on 1)

The method of claim 1, wherein the reference data is aggregated from a plurality of users.

### Claim 3 (depends on 1)

The method of claim 1, wherein the reference data includes measurements of at least one of level of alertness, refreshedness, memory consolidation, relaxedness, cognitive capacity, memory improvement, motor performance, or mood.

### Claim 4 (depends on 1)

The method of claim 1, wherein the reference data includes at least one of magnetoencephalography (MEG) measurements or electroencephalogram (EEG) measurements.

### Claim 5 (depends on 1)

The method of claim 1, wherein the measurement data includes measurements of at least one of level of alertness, refreshedness, memory consolidation, relaxedness, cognitive capacity, memory improvement, motor performance, or mood.

### Claim 6 (depends on 1)

The method of claim 1, wherein the measurement data includes at least one of magnetoencephalography (MEG) measurements or electroencephalogram (EEG) measurements.

### Claim 7 (depends on 1)

The method of claim 1, wherein the at least one stimulation parameter comprises multi-modal stimulation.

### Claim 8 (depends on 7)

The method of claim 7, wherein the multi-modal stimulation comprises at least two of electrical stimuli, tactile stimuli, visual stimuli, and auditory stimuli.

### Claim 9 (depends on 1)

The method of claim 1, wherein the measurement data is collected during a wake period and a sleep period.

### Claim 10 (depends on 1)

The method of claim 1, wherein the modifying of the estimated wake age comprises:
changing a wake age of the at least one user to a target wake age.

### Claim 11

A system comprising:
a communications interface configured to receive measurement data comprising data values representing measurements of neural activity of at least one user;
a processing device configured to:
generate at least one wake model based, at least in part, on reference data, the at least one wake model being configured to identify an estimated wake age of at least one user based on a measurement data;
generate the estimated wake age of the at least one user based, at least in part, on the at least one wake model and the received measurement data;
generate at least one stimulation parameter based, at least in part, on the estimated wake age, the at least one stimulation parameter being configured to modify the estimated wake age of the at least one user; and
a memory device configured to store the at least one wake model and the at least one stimulation parameter;
wherein the communications interface is further configured to apply a stimulus to a brain of the at least one user based on the at least one stimulation parameter.

### Claim 12 (depends on 11)

The system of claim 11, wherein the reference data is aggregated from a plurality of users.

### Claim 13 (depends on 11)

The system of claim 11, wherein the reference data includes measurements of at least one of level of alertness, refreshedness, memory consolidation, relaxedness, cognitive capacity, memory improvement, motor performance, or mood.

### Claim 14 (depends on 11)

The system of claim 11, wherein the reference data includes at least one of magnetoencephalography (MEG) measurements or electroencephalogram (EEG) measurements.

### Claim 15 (depends on 11)

The system of claim 11, wherein the measurement data includes measurements of at least one of level of alertness, refreshedness, memory consolidation, relaxedness, cognitive capacity, memory improvement, motor performance, or mood.

### Claim 16 (depends on 11)

The system of claim 11, wherein the measurement data includes at least one of magnetoencephalography (MEG) measurements or electroencephalogram (EEG) measurements.

### Claim 17 (depends on 11)

The system of claim 11, wherein the at least one stimulation parameter comprises multi-modal stimulation.

### Claim 18 (depends on 17)

The system of claim 17, wherein the multi-modal stimulation comprises at least two of electrical stimuli, tactile stimuli, visual stimuli, and auditory stimuli.

### Claim 19 (depends on 11)

The system of claim 11, wherein the measurement data is collected during a wake period and a sleep period.

### Claim 20 (depends on 11)

The system of claim 11, wherein the modifying of the estimated wake age comprises:
changing a wake age of the at least one user to a target wake age.
