Microneedle structure with high separation yield, device containing the same, and method for manufacturing the same

A microneedle device having a highly-removable microneedle structure, the microneedle device comprising:

• a microneedle structure including:
• a tip tapered downwardly;
• a base extending upwardly from an upper surface of the tip and having an area size in a plan view thereof smaller than an area size in a plan view of an upper surface of the tip;
• and
• a tube surrounding the base and extending upwardly from the upper surface of the tip and beyond an upper surface of the base;
• and
• a microneedle pushing unit including:
• a push pin extending upwardly from the upper surface of the base and beyond an upper surface of the tube;
• and
• a pushing means capable of applying a pushing force to an upper end of the push pin,
• wherein the microneedle device is configured such that when the pushing means applies the force to the upper end of the push pin, a lower end of the push pin applies the force to the base, so that a combination of the tip and the base is removed from the tube, the lower end of the push pin fixes the combination of the tip and the base into a skin, so that the tube is easily removed from the combination.

A method for manufacturing a highly-removable microneedle structure, the method comprising:

• providing a mold a recess defined therein, the recess having a tip shape tapered downwardly;
• filling a curable delivery target substance solution into the recess;
• providing a tube having an inner diameter smaller than an outer diameter of an upper surface of the tip shape;
• contacting the one end of the tube with an upper surface of the delivery target substance solution received in the recess while filling the delivery target substance solution into one end of the tube and closing the other end of the tube;
• or applying a negative pressure to the other end of the tube.